Niacinamide—also known as vitamin B3—is one of the most versatile and gentle ingredients in modern skincare. Celebrated for its ability to calm irritation, refine pores, and brighten dull complexions, this powerhouse nutrient has earned its place in routines for every skin type.

If you’ve ever wondered how to use niacinamide serum effectively, this guide is for you. We’ll walk you through what it does, how to use it properly, and which Acure products to try for the best results—so you can unlock brighter, healthier-looking skin.
What is Niacinamide and Why Is It Beneficial for Your Skin?
Niacinamide is a form of vitamin B3 that plays a critical role in overall skin health. Its benefits are wide-reaching and clinically supported, making it a must-have for both beginners and pros alike.
Niacinamide benefits include:
• Reduces redness and visible inflammation
• Strengthens the skin’s barrier function
• Regulates excess oil production (perfect for acne-prone skin)
• Minimizes the look of pores and fine lines
• Brightens and evens out skin tone
It’s also incredibly gentle, making niacinamide a great fit for even the most sensitive skin types.
How to Use Niacinamide Serum in Your Skincare Routine


When and How to Apply Niacinamide Serum
Niacinamide serums can be used in the morning or evening—or both—depending on your skin’s needs.
Step-by-step application:
- Start with a gentle cleanser.
- Optional: Apply a hydrating toner or mist to prep the skin.
- Dispense 2–3 drops of niacinamide serum into your palm.
- Gently press or pat into the skin (don’t rub!).
- Follow with a moisturizer to lock in hydration.
- In the AM, always finish with SPF 30+ sunscreen.
How to Layer Niacinamide with Other Skincare Ingredients
Niacinamide plays well with:
• Hyaluronic acid: Locks in hydration
• Peptides: Reinforce the skin barrier
• Ceramides: Help maintain moisture
Avoid layering directly with:
• High-concentration vitamin C
• Strong AHAs or BHAs (alternate nights or separate routines)
Who Should Use Niacinamide Serum?
Niacinamide is for everyone, but especially beneficial for:
• Oily or acne-prone skin: Regulates oil and soothes breakouts
• Sensitive skin: Reduces inflammation and supports repair
• Mature skin: Softens fine lines and enhances elasticity
• Uneven tone: Brightens and reduces the look of dark spots
For radiant, even-toned skin, try our Brightening Vitamin C & Niacinamide Serum.
How Long Does It Take to See Results with Niacinamide?
Like all skincare, consistency is key.
• Hydration boost: Noticeable within a few days
• Oil control & redness: ~2–4 weeks
• Brighter tone & smaller pores: 6–8 weeks with daily use
Stick with it—and don’t forget your sunscreen.
Common Mistakes to Avoid When Using Niacinamide Serum
• Using too many actives at once: Keep your routine simple.
• Overapplying serum: A little goes a long way.
• Skipping SPF: Always use sunscreen to protect brightened skin.
• Expecting instant results: Give it time—skin renewal takes consistency.
Best Acure Niacinamide-Infused Products
Ready to upgrade your routine? These Acure bestsellers feature niacinamide for real, noticeable results:
- Brightening Vitamin C Serum: For glow and tone
- Seriously Soothing SPF Day Cream: Soothes and protects
- Ultra Hydrating Plant Ceramide Daily Facial Lotion: Restores barrier and hydration
All Acure products are 100% vegan, cruelty-free, and made without parabens, sulfates, or harsh additives.


Final Tips for Maximizing Niacinamide Benefits
- Use consistently—once or twice daily based on skin type
- Pair with a good moisturizer and daily SPF
- For help building a routine, take the Acure Skincare Quiz